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Trimix Injections at LovMedSpa
For Men

Trimix Injections

A compounded, fast-acting injection that produces a firm erection in minutes — the answer when oral medication is not enough.

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Trimix injection vial and syringe prepared at LovMedSpa

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What is
Trimix?

Trimix is a compounded blend of three medications — alprostadil, papaverine, and phentolamine — that relax the smooth muscle of the penis and open its arteries directly. Because it works locally rather than through the bloodstream, it typically produces an erection within minutes, often regardless of arousal, nerve damage, or how a man responds to pills.

It is widely regarded as one of the most reliable ED treatments short of surgery, and a common option for men whose erectile dysfunction stems from diabetes, prostate surgery, or vascular disease that oral medication has not overcome.

The injection uses an ultra-fine insulin needle placed at the side of the shaft. Most men describe it as a brief pinch. The first dose is given in-office so your provider can find your exact dose and confirm the erection resolves on schedule; after that you self-administer at home as needed.

Trimix is compounded to your prescription by a licensed pharmacy and dosed precisely for you. It is not a one-size product — the ratio and strength are adjusted toward a firm erection that typically lasts around an hour and then subsides on its own.

At LovMedSpa, Trimix is prescribed only after a medical evaluation by our Medical Directors, and every patient is taught the technique in person before taking a single dose home.

Acts directly on penile tissue, so it can produce an erection even in men who get little response from sildenafil or tadalafil.

Onset typically within minutes, with an erection lasting roughly an hour — timing you can plan around.

Your provider titrates the strength in-office so you get exactly enough, not more.

After the first supervised dose, you inject at home with an insulin-sized needle. The whole process takes a minute.

Because little medication enters the bloodstream, the headaches, flushing, and congestion common with pills are less likely.

Frequently
Asked Questions

Everything you need to know before starting Trimix at LovMedSpa.

Does the Trimix injection hurt?

The needle is the same ultra-fine gauge used for insulin. Most men feel a brief pinch and nothing after. The medication itself can cause a mild ache in a minority of patients, which your provider adjusts for by changing the ratio.

How quickly does Trimix work and how long does it last?

An erection typically begins within minutes and lasts around an hour. An erection lasting longer than a few hours should be treated as urgent, which is why we set your dose carefully in-office first.

Do I have to inject myself?

Yes, after the first supervised dose. Your provider walks you through the technique step by step, and you leave with written instructions and a direct line for questions.

How often can I use Trimix?

Your prescription specifies your limits. As a general guide, providers typically advise spacing injections at least a day apart and capping use per week.

Who is a good candidate for Trimix?

Men with moderate to severe erectile dysfunction, especially after prostate surgery or with diabetes or vascular disease, and men who do not respond to or cannot take oral ED medication. A consultation and medical history review come first.

Medically reviewed by Dr. Ahmed Elsoury, MD and Mark Ennett, PhD, CRNA, Medical Directors at LovMedSpa. This page is for education and is not a substitute for a personalized medical consultation.